The Solution Structure of FUS Bound to RNA Reveals a Bipartite Mode of RNA Recognition with Both Sequence and Shape Specificity

Fionna E. Loughlin, Peter J. Lukavsky, Tamara Kazeeva, +10

Molecular Cell

Systems BiologyEngineeringRna RecognitionRna Structure PredictionComputational Biology +9

FUS-dependent liquid–liquid phase separation is important for DNA repair initiation

Brunno Rocha Levone, Silvia C. Lenzken, Marco Antonaci, +11

The Journal of Cell Biology

ChromatinGenome InstabilityRna MetabolismChromatin RemodelingDna Repair Initiation +11

The phase separation-dependent FUS interactome reveals nuclear and cytoplasmic function of liquid–liquid phase separation

Stefan Reber, Daniel Jutzi, Helen Lindsay, +9

Nucleic Acids Research

Llps FusMolecular BiologyCytoskeletonProtein Phase SeparationLiquid-liquid Phase Separation +15

Minor intron splicing is regulated by <scp>FUS</scp> and affected by <scp>ALS</scp> ‐associated <scp>FUS</scp> mutants

Stefan Reber, Jolanda Stettler, Giuseppe Filosa, +9

The EMBO Journal

Transcriptional RegulationNatural SciencesGeneticsRna SplicingMolecular Biology +6

Monomethylated and unmethylated FUS exhibit increased binding to Transportin and distinguish FTLD-FUS from ALS-FUS

Marc Suárez‐Calvet, Manuela Neumann, Thomas Arzberger, +16

Acta Neuropathologica

Distinguish Ftld-fusChemical BiologyUnmethylated Fus ExhibitBiophysicsBiomolecular Engineering

Aberrant interaction of FUS with the U1 snRNA provides a molecular mechanism of FUS induced amyotrophic lateral sclerosis

Daniel Jutzi, Sébastien Campagne, Ralf Schmidt, +12

Nature Communications

Hypertonic Stress Causes Cytoplasmic Translocation of Neuronal, but Not Astrocytic, FUS due to Impaired Transportin Function

Eva‐Maria Hock, Zuzanna Maniecka, Marián Hruška-Plocháň, +11

Cell Reports

FUS/TLS contributes to replication-dependent histone gene expression by interaction with U7 snRNPs and histone-specific transcription factors

Katarzyna Dorota Raczyńska, Marc‐David Ruepp, Aleksandra Brzęk, +7

Nucleic Acids Research

CRISPR-Trap: a clean approach for the generation of gene knockouts and gene replacements in human cells

Stefan Reber, Jonas Mechtersheimer, Sofía Nasif, +6

Molecular Biology of the Cell

EngineeringGeneticsMolecular BiologyTarget GeneTranscriptional Regulation +21

Single-cell RNA-sequencing reveals early mitochondrial dysfunction unique to motor neurons shared across FUS- and TARDBP-ALS

Christoph Schweingruber, Jik Nijssen, Jonas Mechtersheimer, +11

Nature Communications