Docosahexaenoic Acid Reduces Amyloid β Production via Multiple Pleiotropic Mechanisms

Marcus O.W. Grimm, Johanna Kuchenbecker, Sven Grösgen, +9

Journal of Biological Chemistry

Amyloid Precursor ProteinOxidative StressAlzheimer's DiseaseDegenerative PathologyProtein Misfolding +16

Plant Sterols the Better Cholesterol in Alzheimer's Disease? A Mechanistical Study

Verena K. Burg, Heike S. Grimm, Tatjana L. Rothhaar, +13

Journal of Neuroscience

HyperlipidemiaAmyloid Precursor ProteinAlzheimer's DiseaseNeurologyAging-associated Disease +18

Plasmalogen synthesis is regulated via alkyl‐dihydroxyacetonephosphate‐synthase by amyloid precursor protein processing and is affected in Alzheimer’s disease

Marcus O.W. Grimm, Johanna Kuchenbecker, Tatjana L. Rothhaar, +6

Journal of Neurochemistry

Trans fatty acids enhance amyloidogenic processing of the Alzheimer amyloid precursor protein (APP)

Marcus O.W. Grimm, Tatjana L. Rothhaar, Sven Grösgen, +6

The Journal of Nutritional Biochemistry

Neurodegenerative DiseasesAlzheimer's DiseaseBiochemistryDegenerative PathologyProtein Misfolding +2

Plasmalogens Inhibit APP Processing by Directly Affecting<i>γ</i>-Secretase Activity in Alzheimer’s Disease

Tatjana L. Rothhaar, Sven Grösgen, Viola J. Haupenthal, +6

The Scientific World JOURNAL

Impact of Vitamin D on Amyloid Precursor Protein Processing and Amyloid-β Peptide Degradation in Alzheimer's Disease

Marcus O.W. Grimm, Johannes Lehmann, Janine Mett, +10

Neurodegenerative Diseases

Amyloid Precursor Protein (APP) Mediated Regulation of Ganglioside Homeostasis Linking Alzheimer's Disease Pathology with Ganglioside Metabolism

Marcus O.W. Grimm, Eva G. Zinser, Sven Grösgen, +9

PLoS ONE

App CleavageNeurochemical BiomarkersAmyloid Precursor ProteinSynaptic SignalingSocial Sciences +22

Special lipid-based diets alleviate cognitive deficits in the APPswe/PS1dE9 transgenic mouse model of Alzheimer's disease independent of brain amyloid deposition

Hennariikka Koivisto, Marcus O.W. Grimm, Tatjana L. Rothhaar, +12

The Journal of Nutritional Biochemistry

Alzheimer's DiseaseDementiaBrain Amyloid DepositionVascular DementiaNeurochemical Biomarkers +7

Intracellular APP Domain Regulates Serine‐Palmitoyl‐CoA Transferase Expression and Is Affected in Alzheimer′s Disease

Marcus O.W. Grimm, Sven Grösgen, Tatjana L. Rothhaar, +7

International Journal of Alzheimer s Disease

Effect of Different Phospholipids on α-Secretase Activity in the Non-Amyloidogenic Pathway of Alzheimer’s Disease

Marcus O.W. Grimm, Viola J. Haupenthal, Tatjana L. Rothhaar, +6

International Journal of Molecular Sciences

Proteinlipid Interactionα-Secretase ActivityPeptide ScienceLipid MovementAmyloid Precursor Protein +16