Obesity-induced lysine acetylation increases cardiac fatty acid oxidation and impairs insulin signalling

Osama Abo Alrob, Sowndramalingam Sankaralingam, Cary Ma, +11

Cardiovascular Research

AMP-activated protein kinase phosphorylates transcription factors of the CREB family

David M. Thomson, Seth T. Herway, Natasha Fillmore, +4

Journal of Applied Physiology

Cellular PhysiologyTranscriptional RegulationSignaling PathwaySkeletal MuscleAmp-activated Protein Kinase +17

Uncoupling of glycolysis from glucose oxidation accompanies the development of heart failure with preserved ejection fraction

Natasha Fillmore, Jody Levasseur, Arata Fukushima, +4

Molecular Medicine

Effect of Fatty Acids on Human Bone Marrow Mesenchymal Stem Cell Energy Metabolism and Survival

Natasha Fillmore, Alda Huqi, Jagdip S. Jaswal, +8

PLoS ONE

Adult Stem CellMetabolic RemodelingOxidative StressRegenerative MedicineFatty Acids +15

Cardiac branched-chain amino acid oxidation is reduced during insulin resistance in the heart

Natasha Fillmore, Cory S. Wagg, Liyan Zhang, +2

American Journal of Physiology-Endocrinology and Metabolism

Malonyl CoA Decarboxylase Inhibition Improves Cardiac Function Post-Myocardial Infarction

Wei Wang, Liyan Zhang, Pavan K. Battiprolu, +20

JACC Basic to Translational Science

Heart FailureLipid PeroxidationCardiovascular PharmacologyPharmacotherapyMetabolic Remodeling +17

LKB1 and the regulation of malonyl-CoA and fatty acid oxidation in muscle

David M. Thomson, Jacob D. Brown, Natasha Fillmore, +4

American Journal of Physiology-Endocrinology and Metabolism

Cardiac MuscleFatty Acid OxidationCardiovascular FunctionCellular PhysiologyOxidative Stress +18

Sex differences in metabolic cardiomyopathy

Elizabeth Murphy, Georgios Amanakis, Natasha Fillmore, +2

Cardiovascular Research

Heart FailureMetabolic DisorderCardiometabolic RiskCardiovascular FunctionInsulin Signaling +15

Chronic AMP-activated protein kinase activation and a high-fat diet have an additive effect on mitochondria in rat skeletal muscle

Natasha Fillmore, Daniel L. Jacobs, David B. Mills, +2

Journal of Applied Physiology

Metabolic SyndromeEnergy MetabolismMitochondrial BiogenesisBiochemistryMitochondrial Function +12

Thyroid hormone effects on LKB1, MO25, phospho-AMPK, phospho-CREB, and PGC-1α in rat muscle

Devon Jack Branvold, D. R. Allred, D. J. Beckstead, +7

Journal of Applied Physiology

Rat MuscleAmpk ActivityThyroid Hormone TreatmentSkeletal MuscleParathyroid Hormone +15