Brian O. Bachmann

Chapter 8 Methods for In Silico Prediction of Microbial Polyketide and Nonribosomal Peptide Biosynthetic Pathways from DNA Sequence Data

Brian O. Bachmann, Jacques Ravel · Methods in enzymology on CD-ROM/Methods in enzymology · 2009 · 374 citations

Life Sciences, Bioinformatics, Molecular Biology +17

A genomics-guided approach for discovering and expressing cryptic metabolic pathways

Emmanuel Zazopoulos, Ke-xue Huang, Alfredo Staffa et al. · Nature Biotechnology · 2003 · 316 citations

Life Sciences, Bioinformatics, Molecular Biology +14

The Calicheamicin Gene Cluster and Its Iterative Type I Enediyne PKS

Joachim Ahlert, Erica M. Shepard, Natalia Lomovskaya et al. · Science · 2002 · 291 citations

Life Sciences, Biochemistry, Molecular Biology +10

Microbial Genomics as a Guide to Drug Discovery and Structural Elucidation:  ECO-02301, a Novel Antifungal Agent, as an Example

James B. McAlpine, Brian O. Bachmann, Mahmood Piraee et al. · Journal of Natural Products · 2005 · 231 citations

Life Sciences, Microbiology, Molecular Biology +17

Spectroscopic Studies of Substrate Interactions with Clavaminate Synthase 2, a Multifunctional α-KG-Dependent Non-Heme Iron Enzyme:  Correlation with Mechanisms and Reactivities

Jing Zhou, Wendy L. Kelly, Brian O. Bachmann et al. · Journal of the American Chemical Society · 2001 · 150 citations

Life Sciences, Biochemistry, Chemistry +16