Concepedia

Paul Reynen

PR

5

Publications

484

Citations

5

H-Index

1998

Active since

Affiliations

Evotec (Germany)(Current)

Paul Reynen is an author at Evotec (Germany) specializing in neuropharmacology, medicine, and pharmacology.

Top concepts

NeuropharmacologyMedicineBiochemistryPharmacologyNeuroscienceDrug DiscoveryNeurochemistrySynaptic SignalingSynaptic PlasticitySynaptic Transmission

Publications per year

1998–2018

5

Publications

5

Evidence for inverse agonism of SR141716A at human recombinant cannabinoid CB<sub>1</sub> and CB<sub>2</sub> receptors

Sara MacLennan, Paul Reynen, Joyce Kwan et al. · British Journal of Pharmacology · 1998 · 175 citations · Full text

Immunology, Pharmacotherapy, Cannabinoid Pharmacology +16

Positive Allosteric Modulators of GluN2A-Containing NMDARs with Distinct Modes of Action and Impacts on Circuit Function

David H. Hackos, Patrick J. Lupardus, Teddy Grand et al. · Neuron · 2016 · 170 citations · Full text

Glun2a-containing Nmdars, Biochemistry, Natural Sciences +5

Discovery of GluN2A-Selective NMDA Receptor Positive Allosteric Modulators (PAMs): Tuning Deactivation Kinetics via Structure-Based Design

Matthew Volgraf, Benjamin D. Sellers, Yu Jiang et al. · Journal of Medicinal Chemistry · 2016 · 102 citations · Full text

Synaptic Transmission, Neurotransmitter, Synaptic Signaling +28

Chronic GluN2B Antagonism Disrupts Behavior in Wild-Type Mice Without Protecting Against Synapse Loss or Memory Impairment in Alzheimer's Disease Mouse Models

Julien Hanson, William J. Meilandt, Alvin Gogineni et al. · Journal of Neuroscience · 2014 · 25 citations · Full text

Wild-type Mice, Memory Impairment, Pip18 Treatment +22

The GluN2B subunit represents a major functional determinant of NMDA receptors in human induced pluripotent stem cell-derived cortical neurons

Ioana Neagoe, Chang Liu, Alexander Stumpf et al. · Stem Cell Research · 2018 · 12 citations · Full text

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