David H. Hackos

Pannexin-1 Is Required for ATP Release during Apoptosis but Not for Inflammasome Activation

Yan Qu, Shahram Misaghi, Kim Newton et al. · The Journal of Immunology · 2011 · 353 citations · Full text

Inflammasome Activation, Apoptosis, Immunology +24

Structural basis of Nav1.7 inhibition by an isoform-selective small-molecule antagonist

Shivani Ahuja, Susmith Mukund, Lunbin Deng et al. · Science · 2015 · 322 citations · Full text

Voltage-gated Sodium, Molecular Biology, Molecular Pharmacology +18

Cross-species transcriptomic atlas of dorsal root ganglia reveals species-specific programs for sensory function

Min Jung, Michelle Dourado, James Maksymetz et al. · Nature Communications · 2023 · 189 citations · Full text

Structural basis of α-scorpion toxin action on Na _v channels

Thomas Clairfeuille, Alexander Cloake, Daniel T. Infield et al. · Science · 2019 · 187 citations

Structural Basis of Nav1.7 Inhibition by a Gating-Modifier Spider Toxin

Hui Xu, Tianbo Li, Alexis Rohou et al. · Cell · 2019 · 181 citations · Full text

Nav1.7 Inhibition, Molecular Physiology, Toxinology +8