THE CONCISE GUIDE TO PHARMACOLOGY 2021/22: G protein‐coupled receptors

S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, +151

British Journal of Pharmacology

An Autocrine Lactate Loop Mediates Insulin-Dependent Inhibition of Lipolysis through GPR81

Kashan Ahmed, Sorin Tunaru, Cong Tang, +5

Cell Metabolism

Metabolic SyndromeBiochemistryMedicineDiabetesMetabolism +3

The Concise Guide to PHARMACOLOGY 2023/24: G protein-coupled receptors

S P H Alexander, Arthur Christopoulos, Anthony P. Davenport, +162

British Journal of Pharmacology

Drug TargetPeptide ScienceSystem PharmacologySystems PharmacologyMolecular Pharmacology +14

Nicotinic acid– and monomethyl fumarate–induced flushing involves GPR109A expressed by keratinocytes and COX-2–dependent prostanoid formation in mice

Julien Hanson, Andreas Gille, Sabrina Zwykiel, +6

Journal of Clinical Investigation

ImmunologyDermatologyGpr109a-mediated FlushingCellular PhysiologyInflammation +14

Deorphanization of GPR109B as a Receptor for the β-Oxidation Intermediate 3-OH-octanoic Acid and Its Role in the Regulation of Lipolysis

Kashan Ahmed, Sorin Tunaru, Claus-Dieter Langhans, +6

Journal of Biological Chemistry

Metabolic SyndromeBeta-oxidation RatesBiochemistryG Protein-coupled ReceptorMedicine +13

A dynamic and screening-compatible nanoluciferase-based complementation assay enables profiling of individual GPCR–G protein interactions

Céline Laschet, Nadine Dupuis, Julien Hanson

Journal of Biological Chemistry

Different contributions of chemokine N‐terminal features attest to a different ligand binding mode and a bias towards activation of ACKR3/CXCR7 compared with CXCR4 and CXCR3

Martyna Szpakowska, Amanda M. Nevins, Max Meyrath, +13

British Journal of Pharmacology

Identification and pharmacological characterization of succinate receptor agonists

Pierre Geubelle, Julie Gilissen, Sébastien Dilly, +8

British Journal of Pharmacology

GPR101 drives growth hormone hypersecretion and gigantism in mice via constitutive activation of Gs and Gq/11

Dayana Abboud, Adrian Daly, Nadine Dupuis, +8

Nature Communications

Forskolin-free cAMP assay for Gi-coupled receptors

Julie Gilissen, Pierre Geubelle, Nadine Dupuis, +3

Biochemical Pharmacology

Signal TransductionG Protein-coupled ReceptorMedicineFunctional SelectivityForskolin-free Camp +3