Pathways of immune exclusion in metastatic osteosarcoma are associated with inferior patient outcomes

John A. Ligon, Woonyoung Choi, Gady Cojocaru, +20

Journal for ImmunoTherapy of Cancer

The Immunosuppressive Niche of Soft-Tissue Sarcomas is Sustained by Tumor-Associated Macrophages and Characterized by Intratumoral Tertiary Lymphoid Structures

Ling‐Ling Chen, Teniola Oke, Nicholas Siegel, +20

Clinical Cancer Research

The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints

Nicolas L Losa, Michael Cruise, Ada Tam, +16

Journal for ImmunoTherapy of Cancer

Cancer ImmunosurveillanceMedicineImmunologyTumor ImmunityPathology +13

Intratumoral Adaptive Immunosuppression and Type 17 Immunity in Mismatch Repair Proficient Colorectal Tumors

Nicolás J. Llosa, Brandon Luber, Ada Tam, +21

Clinical Cancer Research

Tumorigenicity of hypoxic respiring cancer cells revealed by a hypoxia–cell cycle dual reporter

Anne Le, Zachary E. Stine, Christopher Nguyen, +11

Proceedings of the National Academy of Sciences

Immunopathologic Stratification of Colorectal Cancer for Checkpoint Blockade Immunotherapy

Nicolás J. Llosa, Brandon Luber, Nicholas Siegel, +15

Cancer Immunology Research

Cancer ImmunosurveillanceCpm ScorePd-l1 ExpressionMedicineImmunology +10

Persistent mutant oncogene specific T cells in two patients benefitting from anti-PD-1

Kellie N. Smith, Nicolás J. Llosa, Tricia R. Cottrell, +38

Journal for ImmunoTherapy of Cancer

Revision lumbar fusions have higher rates of reoperation and result in worse clinical outcomes compared to primary lumbar fusions

Mark J. Lambrechts, Gregory R. Toci, Nicholas Siegel, +6

The Spine Journal

Lumbar SpineDegenerative SpineWorse Clinical OutcomesSpinal FusionOutcomes Research +5

Trends in Single-Level Lumbar Fusions Over the Past Decade Using a National Database

Mark J. Lambrechts, Nicholas Siegel, Jeremy C. Heard, +12

World Neurosurgery

Single-level Lumbar FusionsLumbar SpineSpinal Cord InjuryKinesiologyPast Decade +6

Safety of Irradiated Homologous Costal Cartilage Graft in Cleft Rhinoplasty

Hillary E. Jenny, Nicholas Siegel, Robin Yang, +1

Plastic & Reconstructive Surgery