Publication | Open Access
The vigorous immune microenvironment of microsatellite instable colon cancer is balanced by multiple counter-inhibitory checkpoints
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2015
Year
Cancer ImmunosurveillanceMedicineImmunologyTumor ImmunityPathologyColorectal CancerPrimary Colorectal CancerHigh InfiltrationVigorous Immune MicroenvironmentBiological MicroenvironmentsImmune Checkpoint InhibitorImmunotherapyOncologyCancer ResearchTumor MicroenvironmentTumor BiologyMultiple Counter-inhibitory CheckpointsLaser Capture Microdissection/qrt-pcr
Meeting abstracts We examined the immune microenvironment of primary colorectal cancer (CRC) using immunohistochemistry, laser capture microdissection/qRT-PCR, flow cytometry and functional analysis of tumor infiltrating lymphocytes. A subset of CRC displayed high infiltration with activated CD8+