Sean A. Hudson

The thioflavin T fluorescence assay for amyloid fibril detection can be biased by the presence of exogenous compounds

Sean A. Hudson, Heath Ecroyd, Tak W. Kee et al. · FEBS Journal · 2009 · 590 citations

Neurochemical Biomarkers, Polyphenolics, Medicinal Chemistry +18

(−)-Epigallocatechin-3-Gallate (EGCG) Maintains κ-Casein in Its Pre-Fibrillar State without Redirecting Its Aggregation Pathway

Sean A. Hudson, Heath Ecroyd, Francis C. Dehle et al. · Journal of Molecular Biology · 2009 · 136 citations

Pre-fibrillar State, Protein Function, Protein Folding +9

Application of Fragment Screening and Merging to the Discovery of Inhibitors of the <i>Mycobacterium tuberculosis</i> Cytochrome P450 CYP121

Sean A. Hudson, Kirsty J. McLean, Sachin Surade et al. · Angewandte Chemie International Edition · 2012 · 80 citations

Fragment-Based Approaches to the Development of<i>Mycobacterium tuberculosis</i>CYP121 Inhibitors

Madeline E. Kavanagh, Anthony G. Coyne, Kirsty J. McLean et al. · Journal of Medicinal Chemistry · 2016 · 59 citations · Full text

Overcoming the Limitations of Fragment Merging: Rescuing a Strained Merged Fragment Series Targeting <i>Mycobacterium tuberculosis</i> CYP121

Sean A. Hudson, Sachin Surade, Anthony G. Coyne et al. · ChemMedChem · 2013 · 31 citations · Full text

Protein Assembly, Crystal Structure Examination, Internal Strain +17