Kirsty J. McLean

Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium

James Belcher, Kirsty J. McLean, Sarah Matthews et al. · Journal of Biological Chemistry · 2014 · 195 citations · Full text

Life Sciences, Biochemistry, Microbiology +13

Azole antifungals are potent inhibitors of cytochrome P450 mono-oxygenases and bacterial growth in mycobacteria and streptomycetes

Kirsty J. McLean, Ker R. Marshall, Alison Richmond et al. · Microbiology · 2002 · 173 citations

Medicine, Microbiology, Pharmacology +17

P450-Catalyzed Regio- and Diastereoselective Steroid Hydroxylation: Efficient Directed Evolution Enabled by Mutability Landscaping

Carlos G. Acevedo‐Rocha, Charles G. Gamble, Richard Lonsdale et al. · ACS Catalysis · 2018 · 172 citations · Full text

Engineering, Biotechnology, Medicinal Chemistry +15

Atomic Structure of Mycobacterium tuberculosis CYP121 to 1.06 Å Reveals Novel Features of Cytochrome P450

David Leys, Christopher G. Mowat, Kirsty J. McLean et al. · Journal of Biological Chemistry · 2003 · 142 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17

Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of <i>Penicillium chrysogenum</i>

Kirsty J. McLean, Marcus Hans, Ben Meijrink et al. · Proceedings of the National Academy of Sciences · 2015 · 131 citations · Full text

Medicine, Biochemistry, Pharmacology +17