Sachin Surade

The Complex Mechanism of Antimycobacterial Action of 5-Fluorouracil

Vinayak Singh, Miroslav Brecik, Raju Mukherjee et al. · Chemistry & Biology · 2014 · 100 citations

Medicine, Microbiology, Pharmacology +13

Application of Fragment Screening and Merging to the Discovery of Inhibitors of the <i>Mycobacterium tuberculosis</i> Cytochrome P450 CYP121

Sean A. Hudson, Kirsty J. McLean, Sachin Surade et al. · Angewandte Chemie International Edition · 2012 · 81 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

Beyond affinity: selection of antibody variants with optimal biophysical properties and reduced immunogenicity from mammalian display libraries

Michael R. Dyson, Edward W. Masters, Deividas Pazeraitis et al. · mAbs · 2020 · 67 citations · Full text

Pharmacy, Biotechnology, Molecular Biology +17

Fragment-Based Approaches to the Development of<i>Mycobacterium tuberculosis</i>CYP121 Inhibitors

Madeline E. Kavanagh, Anthony G. Coyne, Kirsty J. McLean et al. · Journal of Medicinal Chemistry · 2016 · 60 citations · Full text

Pharmacy, Medicinal Chemistry, Pharmacology +17

Comparative analysis and “expression space” coverage of the production of prokaryotic membrane proteins for structural genomics

Sachin Surade, Markus Klein, Peggy Stolt-Bergner et al. · Protein Science · 2006 · 58 citations · Full text

Life Sciences, Microbiology, Molecular Biology +14