Kenneth W. Drombosky

Tau local structure shields an amyloid-forming motif and controls aggregation propensity

Dailu Chen, Kenneth W. Drombosky, Zhiqiang Hou et al. · Nature Communications · 2019 · 193 citations · Full text

β-Hairpin-Mediated Nucleation of Polyglutamine Amyloid Formation

Karunakar Kar, Cody L. Hoop, Kenneth W. Drombosky et al. · Journal of Molecular Biology · 2013 · 103 citations

Protein Folding, Polyglutamine Amyloid Formation, Natural Sciences +3

Folding Landscape of Mutant Huntingtin Exon1: Diffusible Multimers, Oligomers and Fibrils, and No Detectable Monomer

Bankanidhi Sahoo, Irene Arduini, Kenneth W. Drombosky et al. · PLoS ONE · 2016 · 61 citations · Full text

Mutational analysis implicates the amyloid fibril as the toxic entity in Huntington's disease

Kenneth W. Drombosky, Sascha Rode, Ravi Kodali et al. · Neurobiology of Disease · 2018 · 60 citations · Full text

Toxic Entity, Amyloid Fibril, Alzheimer's Disease +10

d-Polyglutamine Amyloid Recruits l-Polyglutamine Monomers and Kills Cells

Karunakar Kar, Irene Arduini, Kenneth W. Drombosky et al. · Journal of Molecular Biology · 2013 · 43 citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Kills Cells +5