Ivo P. van de Peppel

IVACAFTOR restores FGF19 regulated bile acid homeostasis in cystic fibrosis patients with an S1251N or a G551D gating mutation

Ivo P. van de Peppel, Marcela Doktorova, Gitte Berkers et al. · Journal of Cystic Fibrosis · 2018 · 34 citations · Full text

Life Sciences, Genetics, Molecular Biology +16

Translational model of melphalan-induced gut toxicity reveals drug-host-microbe interactions that drive tissue injury and fever

Hannah R. Wardill, Charlotte E. M. de Mooij, Ana Rita da Silva Ferreira et al. · Cancer Chemotherapy and Pharmacology · 2021 · 30 citations · Full text

Veterinary Medicine, Pathobiology, Pharmacology +17

Efficient reabsorption of transintestinally excreted cholesterol is a strong determinant for cholesterol disposal in mice

Ivo P. van de Peppel, Anna Bertolini, Theo H. van Dijk et al. · Journal of Lipid Research · 2019 · 24 citations · Full text

Pharmacy, Biochemistry, Pharmacology +17

Attenuation of the Hepatoprotective Effects of Ileal Apical Sodium Dependent Bile Acid Transporter (ASBT) Inhibition in Choline-Deficient L-Amino Acid-Defined (CDAA) Diet-Fed Mice

Anuradha Rao, Ivo P. van de Peppel, Sanjeev Gumber et al. · Frontiers in Medicine · 2020 · 18 citations · Full text

Life Sciences, Nutritional Sciences, Pharmacology +17

Defective FXR-FGF15 signaling and bile acid homeostasis in cystic fibrosis mice can be restored by the laxative polyethylene glycol

Anna Bertolini, Ivo P. van de Peppel, Marcela Doktorova-Demmin et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 2019 · 12 citations · Full text

Medicine, Nutrition, Pharmacology +17