Takeshi Kuwata

Regorafenib Plus Nivolumab in Patients With Advanced Gastric or Colorectal Cancer: An Open-Label, Dose-Escalation, and Dose-Expansion Phase Ib Trial (REGONIVO, EPOC1603)

Shota Fukuoka, Hiroki Hara, Naoki Takahashi et al. · Journal of Clinical Oncology · 2020 · 887 citations · Full text

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 785 citations

Cancer Immunosurveillance, Autoimmune Disease, T-regulatory Cell +12

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 752 citations

Cancer Immunosurveillance, Pd-1 Expression, Medicine +11

ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages

Tomohiko Tamura, Tokiko Nagamura‐Inoue, Zeevik Shmeltzer et al. · Immunity · 2000 · 302 citations · Full text

Inflammation, Cytokine, Immune Cell Development +10

Overexpression of tumor necrosis factor (TNF)-α and interferon (IFN)-γ by bone marrow cells from patients with myelodysplastic syndromes

Masanobu Kitagawa, Ichiro Saito, Takeshi Kuwata et al. · Leukemia · 1997 · 259 citations

Inflammation, Hematological Malignancy, Tumor Necrosis Factor +11