Takeshi Kuwata

Regorafenib Plus Nivolumab in Patients With Advanced Gastric or Colorectal Cancer: An Open-Label, Dose-Escalation, and Dose-Expansion Phase Ib Trial (REGONIVO, EPOC1603)

Shota Fukuoka, Hiroki Hara, Naoki Takahashi et al. · Journal of Clinical Oncology · 2020 · 926 citations · Full text

Medicine, Oncology, Pharmacology +17

Lactic acid promotes PD-1 expression in regulatory T cells in highly glycolytic tumor microenvironments

Shogo Kumagai, Shohei Koyama, Kota Itahashi et al. · Cancer Cell · 2022 · 838 citations

Medicine, Immunology, Oncology +17

The PD-1 expression balance between effector and regulatory T cells predicts the clinical efficacy of PD-1 blockade therapies

Shogo Kumagai, Yosuke Togashi, Takahiro Kamada et al. · Nature Immunology · 2020 · 812 citations

Life Sciences, Immunology, Oncology +17

ICSBP Directs Bipotential Myeloid Progenitor Cells to Differentiate into Mature Macrophages

Tomohiko Tamura, Tokiko Nagamura‐Inoue, Zeevik Shmeltzer et al. · Immunity · 2000 · 303 citations · Full text

Life Sciences, Cell Biology, Immunology +10

Lenvatinib plus pembrolizumab in patients with advanced gastric cancer in the first-line or second-line setting (EPOC1706): an open-label, single-arm, phase 2 trial

Akihito Kawazoe, Shota Fukuoka, Yoshiaki Nakamura et al. · The Lancet Oncology · 2020 · 270 citations

Medicine, Oncology, Pharmacology +14