A.J. Powell

Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease

A. Douangamath, D. Fearon, Paul Gehrtz et al. · Nature Communications · 2020 · 541 citations · Full text

Pharmacy, Infectious Diseases, Medicinal Chemistry +15

SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids

Jitske Jansen, Katharina C. Reimer, James S. Nagai et al. · Cell stem cell · 2021 · 266 citations · Full text

Medicine, Infectious Diseases, Pathology +17

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

M. Schuller, G.J. Correy, Stefan Gahbauer et al. · Science Advances · 2021 · 208 citations · Full text

Life Sciences, Biochemistry, Medicinal Chemistry +17

Recognition of structurally diverse substrates by type II 3-hydroxyacyl-CoA dehydrogenase (HADH II)/Amyloid-β binding alcohol dehydrogenase (ABAD)

A.J. Powell, Jon Read, Mark J. Banfield et al. · Journal of Molecular Biology · 2000 · 94 citations

Life Sciences, Biochemistry, Molecular Biology +13

Crystal Structures of Penicillin-binding Protein 2 from Penicillin-susceptible and -resistant Strains of Neisseria gonorrhoeae Reveal an Unexpectedly Subtle Mechanism for Antibiotic Resistance

A.J. Powell, Joshua Tomberg, Ashley M. Deacon et al. · Journal of Biological Chemistry · 2008 · 92 citations · Full text

Life Sciences, Biochemistry, Microbiology +15