D. Fearon

Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease

A. Douangamath, D. Fearon, Paul Gehrtz et al. · Nature Communications · 2020 · 527 citations · Full text

Structure, mechanism and crystallographic fragment screening of the SARS-CoV-2 NSP13 helicase

J.A. Newman, A. Douangamath, Setayesh Yadzani et al. · Nature Communications · 2021 · 232 citations · Full text

Fragment binding to the Nsp3 macrodomain of SARS-CoV-2 identified through crystallographic screening and computational docking

M. Schuller, G.J. Correy, Stefan Gahbauer et al. · Science Advances · 2021 · 198 citations · Full text

Engineering, Nsp3 Macrodomain, Molecular Biology +16

Open science discovery of potent noncovalent SARS-CoV-2 main protease inhibitors

Melissa L. Boby, D. Fearon, Matteo P. Ferla et al. · Science · 2023 · 158 citations · Full text

Iterative computational design and crystallographic screening identifies potent inhibitors targeting the Nsp3 macrodomain of SARS-CoV-2

Stefan Gahbauer, G.J. Correy, M. Schuller et al. · Proceedings of the National Academy of Sciences · 2023 · 117 citations · Full text

Drug Target, Protein Assembly, Biomolecular Structure Prediction +17