Eduardo N. Chini

CD38 Dictates Age-Related NAD Decline and Mitochondrial Dysfunction through an SIRT3-Dependent Mechanism

Juliana Camacho-Pereira, Mariana G. Tarragó, Claudia C.S. Chini et al. · Cell Metabolism · 2016 · 830 citations · Full text

Age-related Nad Decline, Aging, Mitochondrial Function +10

Targeting senescent cells alleviates obesity‐induced metabolic dysfunction

Allyson K. Palmer, Ming Xu, Yi Zhu et al. · Aging Cell · 2019 · 632 citations · Full text

A Potent and Specific CD38 Inhibitor Ameliorates Age-Related Metabolic Dysfunction by Reversing Tissue NAD+ Decline

Mariana G. Tarragó, Claudia C.S. Chini, Karina S. Kanamori et al. · Cell Metabolism · 2018 · 355 citations · Full text

Lifespan Extension, Metabolic Syndrome, Aging +12

Regulation of intracellular levels of NAD: A novel role for CD38

Pınar Aksoy, Thomas A. White, Michael A. Thompson et al. · Biochemical and Biophysical Research Communications · 2006 · 349 citations

Intracellular Levels, Signal Transduction, Biochemistry +11

Flavonoid Apigenin Is an Inhibitor of the NAD+ase CD38

Carlos Escande, Verónica Nin, Nathan L. Price et al. · Diabetes · 2012 · 318 citations · Full text

Cd38 Inhibitors, Metabolic Syndrome, Biosynthesis +14