Junya Imai

Antioxidant and Radical Scavenging Effects of Aged Garlic Extract and its Constituents

Junya Imai, N. Ide, Shinji Nagae et al. · Planta Medica · 1994 · 448 citations

Food Chemistry, Low Level Chemiluminescence, Biochemistry +13

Kynostatin (KNI-227 and -272, highly potent anti-HIV agents: conformationally constrained tripeptide inhibitors of HIV protease containing allophenylnorstatine.

Tsutomu Mimoto, Junya Imai, Sumitsugu Kisanuki et al. · Chemical and Pharmaceutical Bulletin · 1992 · 147 citations · Full text

Bioorganic Chemistry, Transition-state Mimic, Tripeptide Derivatives +17

Rational design and synthesis of a novel class of active site-targeted HIV protease inhibitors containing a hydroxymethylcarbonyl isostere. Use of phenylnorstatine or allophenylnorstatine as a transition-state mimic.

Tsutomu Mimoto, Junya Imai, Shigeki Tanaka et al. · Chemical and Pharmaceutical Bulletin · 1991 · 75 citations · Full text

Medicinal Chemistry, Bioorganic Chemistry, Antiviral Compound +15

Structure-Activity Relationship of Orally Potent Tripeptide-Based HIV Protease Inhibitors Containing Hydroxymethylcarbonyl Isostere.

Tsutomu Mimoto, Naoko Hattori, Haruo Takaku et al. · Chemical and Pharmaceutical Bulletin · 2000 · 45 citations · Full text

Bioorganic Chemistry, Pharmacotherapy, Antiviral Drug +16

Fluoren-9-ylmethyloxycarbonyl (Fmoc) amino acid chloride as an efficient reagent for anchoring Fmoc amino acid to 4-alkoxybenzyl alcohol resin.

Kenichi Akaji, Hideo Tanaka, Hisatomi Itoh et al. · Chemical and Pharmaceutical Bulletin · 1990 · 14 citations · Full text

Engineering, Amino Acids, Biochemistry +10