Favipiravir (T-705) Inhibits Junín Virus Infection and Reduces Mortality in a Guinea Pig Model of Argentine Hemorrhagic Fever

Brian B. Gowen, Terry L. Juelich, Eric J. Sefing, +9

PLoS neglected tropical diseases

Low-dose ribavirin potentiates the antiviral activity of favipiravir against hemorrhagic fever viruses

Jonna B. Westover, Eric J. Sefing, Kevin W. Bailey, +9

Antiviral Research

NeurovirologyMedicineAntiviral ActivityAntiviral Drug DevelopmentAntiviral Therapy +7

Galidesivir limits Rift Valley fever virus infection and disease in Syrian golden hamsters

Jonna B. Westover, Amanda Mathis, Ray Taylor, +7

Antiviral Research

Zoonotic DiseasePathogenesisEmergent VirusPathologyVirology +4

Development of a New Tacaribe Arenavirus Infection Model and Its Use to Explore Antiviral Activity of a Novel Aristeromycin Analog

Brian B. Gowen, Min‐Hui Wong, Deanna Larson, +7

PLoS ONE

Alterations in favipiravir (T-705) pharmacokinetics and biodistribution in a hamster model of viral hemorrhagic fever

Brian B. Gowen, Eric J. Sefing, Jonna B. Westover, +4

Antiviral Research

Hamster ModelViral Hemorrhagic FeverViral PersistenceMedicinePathogenesis +7

Second-Generation Live-Attenuated Candid#1 Vaccine Virus Resists Reversion and Protects against Lethal Junín Virus Infection in Guinea Pigs

Brian B. Gowen, Brady T. Hickerson, Joanne York, +5

Journal of Virology

Enhanced protection against experimental Junin virus infection through the use of a modified favipiravir loading dose strategy

Brian B. Gowen, Jonna B. Westover, Eric J. Sefing, +5

Antiviral Research

VaccinationDose StrategyModified FavipiravirSynthetic VirologyEnhanced Protection +6

Use of Recombinant Adenovirus Vectored Consensus IFN-α to Avert Severe Arenavirus Infection

Brian B. Gowen, Jane Ennis, Andrew Russell, +3

PLoS ONE

Gene TherapiesDef201 TechnologyMolecular VirologyEmerging Infectious DiseasesNeurovirology +12

Single-Dose Intranasal Treatment with DEF201 (Adenovirus Vectored Consensus Interferon) Prevents Lethal Disease Due to Rift Valley Fever Virus Challenge

Brian B. Gowen, Jane Ennis, Kevin W. Bailey, +4

Viruses

Rvfv InfectionSingle-dose Intranasal TreatmentMedicineViral PathogenesisImmunology +12

Type I interferon underlies severe disease associated with Junín virus infection in mice

Brady T. Hickerson, Eric J. Sefing, Kevin W. Bailey, +3

eLife

Viral PathogenesisImmunologyPathologyInnate ImmunityImmune System +17