In Vitro and In Vivo Activities of T-705 against Arenavirus and Bunyavirus Infections

Brian B. Gowen, Min‐Hui Wong, Kie‐Hoon Jung, +5

Antimicrobial Agents and Chemotherapy

Pyrazine Derivative T-705Punta Toro VirusMolecular VirologyVivo ActivitiesNeurovirology +13

Inhibition of influenza virus infections in mice by GS4104, an orally effective influenza virus neuraminidase inhibitor

Robert W. Sidwell, John H. Huffman, Dale L. Barnard, +5

Antiviral Research

VaccinationInfluenza Virus InfectionsMedicineAntiviral TherapyVirology +2

Efficacy of Orally Administered T-705 on Lethal Avian Influenza A (H5N1) Virus Infections in Mice

Robert W. Sidwell, Dale L. Barnard, Craig W. Day, +5

Antimicrobial Agents and Chemotherapy

VaccinationMedicineLung ConsolidationViral PathogenesisImmunology +13

TLR3 Deletion Limits Mortality and Disease Severity due to Phlebovirus Infection

Brian B. Gowen, Justin D. Hoopes, Min‐Hui Wong, +5

The Journal of Immunology

TLR3 Is Essential for the Induction of Protective Immunity against Punta Toro Virus Infection by the Double-Stranded RNA (dsRNA), Poly(I:C12U), but not Poly(I:C): Differential Recognition of Synthetic dsRNA Molecules

Brian B. Gowen, Min‐Hui Wong, Kie‐Hoon Jung, +5

The Journal of Immunology

Effects of the Combination of Favipiravir (T-705) and Oseltamivir on Influenza A Virus Infections in Mice

Donald F. Smee, Brett L. Hurst, Min‐Hui Wong, +4

Antimicrobial Agents and Chemotherapy

Effects of cidofovir on the pathogenesis of a lethal vaccinia virus respiratory infection in mice

Donald F. Smee, Kevin W. Bailey, Min‐Hui Wong, +1

Antiviral Research

VaccinationVaccine DevelopmentImmunologyViral PathogenesisAntiviral Response +4

Treatment of Late Stage Disease in a Model of Arenaviral Hemorrhagic Fever: T-705 Efficacy and Reduced Toxicity Suggests an Alternative to Ribavirin

Brian B. Gowen, Donald F. Smee, Min‐Hui Wong, +6

PLoS ONE

T-705 EfficacySubstituted PyrazineImmunologyViral PathogenesisAntiviral Drug +14

Efficacy of favipiravir (T-705) and T-1106 pyrazine derivatives in phlebovirus disease models

Brian B. Gowen, Min‐Hui Wong, Kie‐Hoon Jung, +3

Antiviral Research

Molecular VirologyPhlebovirus Disease ModelsMedicineDrug DiscoveryAntiviral Drug Development +7

Activities of Oseltamivir and Ribavirin Used Alone and in Combination against Infections in Mice with Recent Isolates of Influenza a (H1N1) and B Viruses

Donald F. Smee, Min‐Hui Wong, Kevin W. Bailey, +1

Antiviral chemistry & chemotherapy