J. Wilson

Regulation of p53 activity through lysine methylation

Sergei Chuikov, Julia K. Kurash, J. Wilson et al. · Nature · 2004 · 805 citations

Chromatin, Lysine Methylation, Medicine +7

Structural basis of oncogenic histone H3K27M inhibition of human polycomb repressive complex 2

N. Justin, Ying Zhang, Cataldo Tarricone et al. · Nature Communications · 2016 · 398 citations · Full text

Structure and catalytic mechanism of the human histone methyltransferase SET7/9

Bing Xiao, Chun Jing, J. Wilson et al. · Nature · 2003 · 376 citations

Histone Modifications, Chromatin, Chromatin Structure +14

Structural Basis for the Requirement of Additional Factors for MLL1 SET Domain Activity and Recognition of Epigenetic Marks

Stacey M. Southall, P.S. Wong, Zain Odho et al. · Molecular Cell · 2009 · 228 citations · Full text

Chromatin, Functional Genomics, Chromatin Remodeling +15

Identification of (<i>R</i>)-<i>N</i>-((4-Methoxy-6-methyl-2-oxo-1,2-dihydropyridin-3-yl)methyl)-2-methyl-1-(1-(1-(2,2,2-trifluoroethyl)piperidin-4-yl)ethyl)-1<i>H</i>-indole-3-carboxamide (CPI-1205), a Potent and Selective Inhibitor of Histone Methyltransferase EZH2, Suitable for Phase I Clinical Trials for B-Cell Lymphomas

Rishi G. Vaswani, Victor Gehling, Les A. Dakin et al. · Journal of Medicinal Chemistry · 2016 · 214 citations · Full text