Concepedia

Irmgard Hofmann

IH

8

Publications

986

Citations

8

H-Index

2004

Active since

Affiliations

Novartis (Switzerland)(Current)

Novartis Institutes for BioMedical Research

Novartis (United States)

MRC Laboratory of Molecular Biology

Boehringer Ingelheim (Austria)

Irmgard Hofmann is an author at Novartis (Switzerland) specializing in medicine, cell biology, and cell signaling.

Top concepts

MedicineCell BiologyCell SignalingNatural SciencesSignal TransductionOncologyPathologyTumor BiologyCancer BiologyCancer Research

Publications per year

2004–2022

8

Publications

8

Specific apoptosis induction by the dual PI3K/mTor inhibitor NVP-BEZ235 in HER2 amplified and PIK3CA mutant breast cancer cells

Saskia M. Brachmann, Irmgard Hofmann, Christian Schnell et al. · Proceedings of the National Academy of Sciences · 2009 · 316 citations · Full text

Dual Pi3k/mtor Inhibitor, Breast Oncology, Oncology +15

An N-terminally acetylated Arf-like GTPase is localised to lysosomes and affects their motility

Irmgard Hofmann, Sean Munro · Journal of Cell Science · 2006 · 238 citations

Molecular Biology, Cytoskeleton, Cellular Physiology +19

Crosstalk of the mitotic spindle assembly checkpoint with p53 to prevent polyploidy

Celia Vogel, Anne Kienitz, Irmgard Hofmann et al. · Oncogene · 2004 · 167 citations

Chromatin, Genome Instability, Cell Division +10

The Arl4 Family of Small G Proteins Can Recruit the Cytohesin Arf6 Exchange Factors to the Plasma Membrane

Irmgard Hofmann, Amanda L. Thompson, Christopher M. Sanderson et al. · Current Biology · 2007 · 128 citations · Full text

Arl4 Family, Protein Function, Signal Transduction +11

K-RAS Mutant Pancreatic Tumors Show Higher Sensitivity to MEK than to PI3K Inhibition In Vivo

Irmgard Hofmann, Andreas Weiss, Gaëlle Elain et al. · PLoS ONE · 2012 · 68 citations · Full text

Pathology, Cancer Biology, Tumor Biology +17

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