Antibody against early driver of neurodegeneration cis P-tau blocks brain injury and tauopathy

Asami Kondo, Koorosh Shahpasand, Rebekah Mannix, +19

Nature

Alzheimer's DiseaseAutoimmune DiseaseMedicineImmunologyProteinopathies +11

Concussion, microvascular injury, and early tauopathy in young athletes after impact head injury and an impact concussion mouse model

Chad A. Tagge, Andrew Fisher, Olga Minaeva, +43

Brain

Active Pin1 is a key target of all-trans retinoic acid in acute promyelocytic leukemia and breast cancer

Shuo Wei, Shingo Kozono, Lev M. Kats, +22

Nature Medicine

Active Pin1Mixed-phenotype Acute LeukemiaBreast CancerTumor SuppressorRadiation Oncology +4

Cis P-tau is induced in clinical and preclinical brain injury and contributes to post-injury sequelae

Önder Albayram, Asami Kondo, Rebekah Mannix, +17

Nature Communications

Pin1 cysteine-113 oxidation inhibits its catalytic activity and cellular function in Alzheimer's disease

Chun-Hau Chen, Wenzong Li, Rukhsana Sultana, +14

Neurobiology of Disease

Alzheimer's DiseaseBiochemistryMedicineDementiaNatural Sciences +11

TRANSPLANTATION OF HIGHLY DIFFERENTIATED IMMORTALIZED HUMAN HEPATOCYTES TO TREAT ACUTE LIVER FAILURE 1

Naoya Kobayashi, Masahiro Miyazaki, Kenichi Fukaya, +7

Transplantation

Cis P-tau underlies vascular contribution to cognitive impairment and dementia and can be effectively targeted by immunotherapy in mice

Chenxi Qiu, Önder Albayram, Asami Kondo, +22

Science Translational Medicine

A Distinct Role for Pin1 in the Induction and Maintenance of Pluripotency

Mayuko Nishi, Hidenori Akutsu, Shinji Masui, +12

Journal of Biological Chemistry

Adenovirus type 5 with modified hexons induces robust transgene‐specific immune responses in mice with pre‐existing immunity against adenovirus type 5

Shinya Abe, Kenji Okuda, Takehiro Ura, +6

The Journal of Gene Medicine

Morphological and biochemical analyses on fibroblasts and self-produced collagens in a novel three-dimensional culture

Osamu Ishikawa, Asami Kondo, K. Okada, +2

British Journal of Dermatology

Tissue EngineeringEngineeringBacterial CollagenaseBiofabricationCell Culture +19