Simone L. Popp

ADAM17 is the main sheddase for the generation of human triggering receptor expressed in myeloid cells (hTREM2) ectodomain and cleaves TREM2 after Histidine 157

Dominik Feuerbach, Patrick Schindler, Carmen Barske et al. · Neuroscience Letters · 2017 · 179 citations

Histidine 157, Cleaves Trem2, G Protein-coupled Receptor +7

Improved cancer immunotherapy by a CD25-mimobody conferring selectivity to human interleukin-2

Natalia Arenas-Ramirez, Chao Zou, Simone L. Popp et al. · Science Translational Medicine · 2016 · 128 citations

Highly reduced binding to high and low affinity mouse Fc gamma receptors by L234A/L235A and N297A Fc mutations engineered into mouse IgG2a

E. Arduin, Shilpi Arora, P.R. Bamert et al. · Molecular Immunology · 2014 · 80 citations

Knockout Mouse, Signal Transduction, Mouse Igg2a +9

Antiestrogens Induce Transforming Growth Factor β–Mediated Immunosuppression in Breast Cancer

Christian Joffroy, Miriam Buck, Matthias B. Stope et al. · Cancer Research · 2010 · 72 citations · Full text

Cancer Immunosurveillance, Breast Oncology, Medicine +15

Structural Dynamics of the DnaK–Peptide Complex

Simone L. Popp, Lars Packschies, Nicole Radzwill et al. · Journal of Molecular Biology · 2005 · 36 citations

Protein Assembly, Natural Sciences, Molecular Biology +3