Frédéric J. Zécri

Persistent signaling induced by FTY720-phosphate is mediated by internalized S1P1 receptors

Florian Müllershausen, Frédéric J. Zécri, Cihan Cetin et al. · Nature Chemical Biology · 2009 · 369 citations

Life Sciences, Cell Biology, Molecular Biology +7

Predictive Model for Site-Selective Aryl and Heteroaryl C–H Functionalization via Organic Photoredox Catalysis

Kaila A. Margrey, Joshua B. McManus, Simone Bonazzi et al. · Journal of the American Chemical Society · 2017 · 178 citations

Natural Sciences, Chemistry, Medicinal Chemistry +17

Discovery and characterization of a selective IKZF2 glue degrader for cancer immunotherapy

Simone Bonazzi, Eva d’Hennezel, Rohan E. J. Beckwith et al. · Cell chemical biology · 2023 · 156 citations · Full text

Medicine, Medicinal Chemistry, Oncology +14

Novel Immunomodulator FTY720 Is Phosphorylated in Rats and Humans To Form a Single Stereoisomer. Identification, Chemical Proof, and Biological Characterization of the Biologically Active Species and Its Enantiomer

Rainer Albert, Klaus Hinterding, Volker Brinkmann et al. · Journal of Medicinal Chemistry · 2005 · 150 citations · Full text

Pharmacy, Biochemistry, Medicinal Chemistry +12

Discovery, Preclinical Characterization, and Early Clinical Activity of JDQ443, a Structurally Novel, Potent, and Selective Covalent Oral Inhibitor of KRASG12C

Andreas Weiss, Edwige Lorthiois, Louise Barys et al. · Cancer Discovery · 2022 · 134 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +13