Astrid Brüggerhoff

Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases

Dominik Büttner, Jan S. Kramer, Franca‐Maria Klingler et al. · ACS Infectious Diseases · 2017 · 59 citations

Drug Target, Antimicrobial Chemotherapy, Pharmaceutical Chemistry +19

<i>N</i>-Benzylbenzamides: A Novel Merged Scaffold for Orally Available Dual Soluble Epoxide Hydrolase/Peroxisome Proliferator-Activated Receptor γ Modulators

René Blöcher, Christina Lamers, Sandra K. Wittmann et al. · Journal of Medicinal Chemistry · 2015 · 49 citations · Full text

Design, synthesis and evaluation of 2-aminothiazole derivatives as sphingosine kinase inhibitors

Dominik Walter Vogt, Júlia Wéber, Katja Ihlefeld et al. · Bioorganic & Medicinal Chemistry · 2014 · 43 citations · Full text

Combinatorial Chemistry, Medicinal Chemistry, Biochemistry +9

Multi-dimensional target profiling of N,4-diaryl-1,3-thiazole-2-amines as potent inhibitors of eicosanoid metabolism

Carmen B. Rödl, Dominik Walter Vogt, Simon B.M. Kretschmer et al. · European Journal of Medicinal Chemistry · 2014 · 37 citations · Full text

Multi-dimensional Target Profiling, Eicosanoid Metabolism, Drug Target +7

From a Multipotent Stilbene to Soluble Epoxide Hydrolase Inhibitors with Antiproliferative Properties

Estel la Buscató, Dominik Büttner, Astrid Brüggerhoff et al. · ChemMedChem · 2013 · 29 citations

Soluble Epoxide Hydrolase, Combinatorial Chemistry, Medicinal Chemistry +14