Franca‐Maria Klingler

Approved Drugs Containing Thiols as Inhibitors of Metallo-β-lactamases: Strategy To Combat Multidrug-Resistant Bacteria

Franca‐Maria Klingler, Thomas A. Wichelhaus, Denia Frank et al. · Journal of Medicinal Chemistry · 2015 · 151 citations

Antimicrobial Chemotherapy, Antibiotic Resistance, Thermal Shift +21

Chemical space docking enables large-scale structure-based virtual screening to discover ROCK1 kinase inhibitors

Paul Beroza, James J. Crawford, Oleg Ganichkin et al. · Nature Communications · 2022 · 102 citations · Full text

Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases

Dominik Büttner, Jan S. Kramer, Franca‐Maria Klingler et al. · ACS Infectious Diseases · 2017 · 59 citations

Drug Target, Antimicrobial Chemotherapy, Pharmaceutical Chemistry +19

NSAIDs Ibuprofen, Indometacin and Diclofenac do not interact with Farnesoid X Receptor

Jurema Schmidt, Franca‐Maria Klingler, Ewgenji Proschak et al. · Scientific Reports · 2015 · 57 citations · Full text

Dual-Target Virtual Screening by Pharmacophore Elucidation and Molecular Shape Filtering

Daniel Moser, Joanna Wiśniewska, Steffen Hahn et al. · ACS Medicinal Chemistry Letters · 2012 · 47 citations · Full text

Drug Target, Hit Identification, Pharmacotherapy +20