Jan S. Kramer

Nonacidic Farnesoid X Receptor Modulators

Daniel Flesch, Sun-Yee Cheung, Jurema Schmidt et al. · Journal of Medicinal Chemistry · 2017 · 83 citations · Full text

Signal Transduction, Biochemistry, Functional Selectivity +15

Severe SMA mice show organ impairment that cannot be rescued by therapy with the HDACi JNJ-26481585

Julia Schreml, Mario Paterno, Lutz Garbes et al. · European Journal of Human Genetics · 2012 · 72 citations · Full text

Knockout Mouse, Autoimmune Disease, Hdaci Jnj-26481585 +6

Challenges in the Development of a Thiol-Based Broad-Spectrum Inhibitor for Metallo-β-Lactamases

Dominik Büttner, Jan S. Kramer, Franca‐Maria Klingler et al. · ACS Infectious Diseases · 2017 · 59 citations

Drug Target, Antimicrobial Chemotherapy, Pharmaceutical Chemistry +19

Dendritic Fluoroalcohols as Catalysts for Alkene Epoxidation with Hydrogen Peroxide

Albrecht Berkessel, Jan S. Kramer, Florian Mummy et al. · Angewandte Chemie International Edition · 2012 · 56 citations

Chemical Engineering, Novel Organocatalysts, Mild Catalytic Epoxidation +11

Discovery of the First in Vivo Active Inhibitors of the Soluble Epoxide Hydrolase Phosphatase Domain

Jan S. Kramer, Stefano Woltersdorf, Thomas Duflot et al. · Journal of Medicinal Chemistry · 2019 · 43 citations · Full text