Spencer E. Brightman

Toll-like receptor 8 agonist nanoparticles mimic immunomodulating effects of the live BCG vaccine and enhance neonatal innate and adaptive immune responses

David J. Dowling, Evan A. Scott, Annette Scheid et al. · Journal of Allergy and Clinical Immunology · 2017 · 147 citations · Full text

Pharmacy, Immunology, Pharmaceutics +17

Neoantigen-specific stem cell memory-like CD4+ T cells mediate CD8+ T cell-dependent immunotherapy of MHC class II-negative solid tumors

Spencer E. Brightman, Angelica Becker, Rukman R. Thota et al. · Nature Immunology · 2023 · 79 citations · Full text

Life Sciences, Immunology, Oncology +14

Linked CD4+/CD8+ T cell neoantigen vaccination overcomes immune checkpoint blockade resistance and enables tumor regression

Joseph S. Dolina, Joey Lee, Spencer E. Brightman et al. · Journal of Clinical Investigation · 2023 · 67 citations · Full text

Life Sciences, Immunology, Oncology +17

Identification and Characterization of Stimulator of Interferon Genes As a Robust Adjuvant Target for Early Life Immunization

Francesco Borriello, Carlo Pietrasanta, Jacqueline C.Y. Lai et al. · Frontiers in Immunology · 2017 · 47 citations · Full text

Veterinary Medicine, Immunology, Infectious Diseases +17

Adjuvant-induced Human Monocyte Secretome Profiles Reveal Adjuvant- and Age-specific Protein Signatures

Djin‐Ye Oh, David J. Dowling, Saima Ahmed et al. · Molecular & Cellular Proteomics · 2016 · 33 citations · Full text

Life Sciences, Biochemistry, Immunology +17