Niels C. Adams

Recognition of single-stranded RNA viruses by Toll-like receptor 7

Jennifer M. Lund, Lena Alexopoulou, Ayuko Sato et al. · Proceedings of the National Academy of Sciences · 2004 · 1.8K citations · Full text

Life Sciences, Immunology, Molecular Biology +17

Haploinsufficiency of delta-like 4 ligand results in embryonic lethality due to major defects in arterial and vascular development

Nicholas W. Gale, Melissa G. Dominguez, Irene Noguera et al. · Proceedings of the National Academy of Sciences · 2004 · 597 citations · Full text

Life Sciences, Developmental Biology, Genetics +17

High-throughput engineering of the mouse genome coupled with high-resolution expression analysis

David M. Valenzuela, Andrew Murphy, David Frendewey et al. · Nature Biotechnology · 2003 · 593 citations

Life Sciences, Genetics, Molecular Biology +16

Genome-wide Generation and Systematic Phenotyping of Knockout Mice Reveals New Roles for Many Genes

Jacqueline K. White, Anna-Karin Gerdin, Natasha A. Karp et al. · Cell · 2013 · 542 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

F0 generation mice fully derived from gene-targeted embryonic stem cells allowing immediate phenotypic analyses

William Poueymirou, Wojtek Auerbach, David Frendewey et al. · Nature Biotechnology · 2006 · 241 citations · Full text

Life Sciences, Developmental Biology, Genetics +14