Effect of calorie restriction on the metabolic history of chronologically aging yeast

Alexander A. Goldberg, Simon D. Bourque, Pavlo Kyryakov, +10

Experimental Gerontology

BiologyEnergy MetabolismAgingHealth SciencesLongevity +10

Chemical genetic screen identifies lithocholic acid as an anti-aging compound that extends yeast chronological life span in a TOR-independent manner, by modulating housekeeping longevity assurance processes

Alexander A. Goldberg, Vincent R. Richard, Pavlo Kyryakov, +10

Aging

Purification of Mitochondria from Yeast Cells

Christopher Gregg, Pavlo Kyryakov, Vladimir I. Titorenko

Journal of Visualized Experiments

Caloric Restriction Extends Yeast Chronological Lifespan by Altering a Pattern of Age-Related Changes in Trehalose Concentration

Pavlo Kyryakov, Adam Beach, Vincent R. Richard, +4

Frontiers in Physiology

A signal from inside the peroxisome initiates its division by promoting the remodeling of the peroxisomal membrane

Tong Guo, Christopher Gregg, Tatiana Boukh‐Viner, +10

The Journal of Cell Biology

A novel function of lipid droplets in regulating longevity

Alexander A. Goldberg, Simon D. Bourque, Pavlo Kyryakov, +8

Biochemical Society Transactions

BiologyDynamic OrganellesLongevity RegulationLifespan ExtensionAnti-aging +11

Lithocholic acid extends longevity of chronologically aging yeast only if added at certain critical periods of their lifespan

Michelle T. Burstein, Pavlo Kyryakov, Adam Beach, +7

Cell Cycle

Anti-agingAgingCell CycleBiogerontologyChronological Aging +18

Lithocholic bile acid accumulated in yeast mitochondria orchestrates a development of an anti-aging cellular pattern by causing age-related changes in cellular proteome

Adam Beach, Vincent R. Richard, Simon D. Bourque, +9

Cell Cycle

MitophagyGeneticsMolecular BiologyLithocholic Bile AcidOxidative Stress +17

Purification of Mitochondria from Yeast Cells

Christopher Gregg, Pavlo Kyryakov, Vladimir I. Titorenko

Journal of Visualized Experiments

Membrane FusionOther OrganellesBiochemistryMitochondrial FunctionMedicine +13

Mechanism of liponecrosis, a distinct mode of programmed cell death

Vincent R. Richard, Adam Beach, Amanda Piano, +15

Cell Cycle

OxysterolBiochemistryMitochondrial FunctionLiponecrotic PcdLipid Peroxidation +13