Jonathan Vanhoutte

Human Atherosclerotic Plaque Alternative Macrophages Display Low Cholesterol Handling but High Phagocytosis Because of Distinct Activities of the PPARγ and LXRα Pathways

Giulia Chinetti, Morgane Baron, Mohamed Amine Bouhlel et al. · Circulation Research · 2011 · 367 citations · Full text

Nuclear Receptor Subfamily 1 Group D Member 1 Regulates Circadian Activity of NLRP3 Inflammasome to Reduce the Severity of Fulminant Hepatitis in Mice

Benoît Pourcet, Mathilde Zecchin, Lise Ferri et al. · Gastroenterology · 2017 · 207 citations · Full text

Inflammation, Fulminant Hepatitis, Signal Transduction +11

The novel selective PPARα modulator (SPPARMα) pemafibrate improves dyslipidemia, enhances reverse cholesterol transport and decreases inflammation and atherosclerosis

Nathalie Hennuyer, Isabelle Duplan, Charlotte Paquet et al. · Atherosclerosis · 2016 · 128 citations

Inflammation, Metabolic Syndrome, Molecular Pharmacology +12

p16INK4a deficiency promotes IL-4–induced polarization and inhibits proinflammatory signaling in macrophages

Céline Cudejko, Kristiaan Wouters, Lucı́a Fuentes et al. · Blood · 2011 · 123 citations · Full text

Interspecies NASH disease activity whole-genome profiling identifies a fibrogenic role of PPARα-regulated dermatopontin

Philippe Lefèbvre, Fanny Lalloyer, Eric Baugé et al. · JCI Insight · 2017 · 117 citations · Full text

Genetics, Immune Regulation, Immunology +30