Nathalie G. M. Thielen

Increased IL-6 receptor expression and signaling in ageing cartilage can be explained by loss of TGF-β-mediated IL-6 receptor suppression

Renske Wiegertjes, Nathalie G. M. Thielen, A. van Caam et al. · Osteoarthritis and Cartilage · 2021 · 24 citations · Full text

Osteoarthritis-Related Inflammation Blocks TGF-β’s Protective Effect on Chondrocyte Hypertrophy via (de)Phosphorylation of the SMAD2/3 Linker Region

Nathalie G. M. Thielen, M. Neefjes, Renske Wiegertjes et al. · International Journal of Molecular Sciences · 2021 · 23 citations · Full text

Immunology, Orthopaedic Surgery, Inflammatory Arthritis +20

Identification of Transcription Factors Responsible for a Transforming Growth Factor-β-Driven Hypertrophy-like Phenotype in Human Osteoarthritic Chondrocytes

Nathalie G. M. Thielen, M. Neefjes, E.L. Vitters et al. · Cells · 2022 · 14 citations · Full text

Separating friend from foe: Inhibition of TGF-β-induced detrimental SMAD1/5/9 phosphorylation while maintaining protective SMAD2/3 signaling in OA chondrocytes

Nathalie G. M. Thielen, A. van Caam, Henk M. van Beuningen et al. · Osteoarthritis and Cartilage · 2023 · 13 citations · Full text

Pulmonary inflammation-induced loss and subsequent recovery of skeletal muscle mass require functional poly-ubiquitin conjugation

Judith Ceelen, Annemie M.W.J. Schols, Nathalie G. M. Thielen et al. · Respiratory Research · 2018 · 11 citations · Full text