Mitochondrial DNA–Deletion Mutations Accumulate Intracellularly to Detrimental Levels in Aged Human Skeletal Muscle Fibers

Entela Bua, Jody Johnson, Allen Herbst, +4

The American Journal of Human Genetics

Mitochondrial MyopathyMuscle PhysiologyMitochondrial FunctionSkeletal MuscleGenetics +7

Accumulation of Mitochondrial DNA Deletion Mutations in Aged Muscle Fibers: Evidence for a Causal Role in Muscle Fiber Loss

Allen Herbst, Jeong W. Pak, Debbie McKenzie, +3

The Journals of Gerontology Series A

Mitochondrial MyopathyMechanobiologyMuscle Fiber LossAgingMitochondrial Function +13

Prion Protein Polymorphisms Affect Chronic Wasting Disease Progression

Chad Johnson, Allen Herbst, Camilo Duque-Velasquez, +4

PLoS ONE

GeneticsHuman PolymorphismGenetic EpidemiologyImmunologyPathology +14

Apoptosis and necrosis mediate skeletal muscle fiber loss in age‐induced mitochondrial enzymatic abnormalities

Nashwa Cheema, Allen Herbst, Debbie McKenzie, +1

Aging Cell

Deer Prion Proteins Modulate the Emergence and Adaptation of Chronic Wasting Disease Strains

Camilo Duque Velásquez, Chiye Kim, Allen Herbst, +5

Journal of Virology

Mitochondrial DNA mutations as a fundamental mechanism in physiological declines associated with aging

Jeong W. Pak, Allen Herbst, Entela Bua, +3

Aging Cell

Latent mitochondrial <scp>DNA</scp> deletion mutations drive muscle fiber loss at old age

Allen Herbst, Jonathan Wanagat, Nashwa Cheema, +3

Aging Cell

Mitochondrial MyopathyMuscle Fiber LossOld AgeAgingMitochondrial Function +13

Mitochondrial DNA deletion mutations increase exponentially with age in human skeletal muscle

Allen Herbst, Cathy C. Lee, Amy R. Vandiver, +6

Aging Clinical and Experimental Research

Mitochondrial FunctionHuman Skeletal MuscleLongevityGeneticsPhysiology +4

Chronic Wasting Disease Prion Strain Emergence and Host Range Expansion

Allen Herbst, Camilo Duque Velásquez, Elizabeth Triscott, +2

Emerging infectious diseases

Prion protein polymorphisms associated with reduced CWD susceptibility limit peripheral PrPCWD deposition in orally infected white-tailed deer

Alicia Otero, Camilo Duque Velásquez, Chad Johnson, +5

BMC Veterinary Research