Linda James

K- and N-Ras Are Geranylgeranylated in Cells Treated with Farnesyl Protein Transferase Inhibitors

David B. Whyte, Paul T. Kirschmeier, Tish Hockenberry et al. · Journal of Biological Chemistry · 1997 · 881 citations · Full text

Medicine, Molecular Biology, Oncology +16

Farnesyl Transferase Inhibitors Block the Farnesylation of CENP-E and CENP-F and Alter the Association of CENP-E with the Microtubules

Hena R. Ashar, Linda James, Kimberly Gray et al. · Journal of Biological Chemistry · 2000 · 321 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Characterization of Ha-Ras, N-Ras, Ki-Ras4A, and Ki-Ras4B as in Vitro Substrates for Farnesyl Protein Transferase and Geranylgeranyl Protein Transferase Type I

Fang L. Zhang, Paul T. Kirschmeier, Donna Carr et al. · Journal of Biological Chemistry · 1997 · 202 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +12

Novel Tricyclic Inhibitors of Farnesyl Protein Transferase

W. Robert Bishop, Richard Bond, Joanne Petrin et al. · Journal of Biological Chemistry · 1995 · 155 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +14

Ras oncoprotein inhibitors: The discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex

Arthur G. Taveras, Stacy Remiszewski, Ronald J. Doll et al. · Bioorganic & Medicinal Chemistry · 1997 · 123 citations

Medicine, Molecular Biology, Oncology +17