Donna Carr - Concepedia

Concepedia

Author

Donna Carr

Merck & Co., Inc., Rahway, NJ, USA (United States)

Also Known As

D. Carr, Donna Carr, Donna M. Carr

42

Publications

2.8K

Citations

17

H-Index

45

Concepts

All Affiliations

Merck & Co., Inc., Rahway, NJ, USA (United States)WuXi AppTec (China)AGCO (United Kingdom)AIL Research (United States)United States Military Academy

DC

About

Donna Carr is an author at Merck & Co., Inc., Rahway, NJ, USA (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	14	16	1.4K
2	Natural Sciences	9	9	862
3	Biochemistry	8	8	451
4	Health Sciences	2	2	720
5	Engineering	1	1	43

Donna Carr

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25

Publications

2.8K

Citations

17

H-Index

	Year	Citations
Discovery of a Novel ERK Inhibitor with Activity in Models of Acquired Resistance to BRAF and MEK Inhibitors Erick J. Morris, Sharda Jha, Clifford R. Restaino, Cancer Discovery PharmacotherapyTumor BiologyDrug ResistanceMek InhibitorsReceptor Tyrosine Kinase	2013	673
Selective small-molecule inhibition of an RNA structural element John A. Howe, Hao Wang, Thierry Fischmann, Nature Natural SciencesRna Structure PredictionSelective Small-molecule InhibitionRna BiologyMolecular Biology	2015	411
Farnesyl Transferase Inhibitors Block the Farnesylation of CENP-E and CENP-F and Alter the Association of CENP-E with the Microtubules Hena R. Ashar, Linda James, Kimberly Gray, Journal of Biological Chemistry	2000	320
Characterization of Ha-Ras, N-Ras, Ki-Ras4A, and Ki-Ras4B as in Vitro Substrates for Farnesyl Protein Transferase and Geranylgeranyl Protein Transferase Type I Fang L. Zhang, Paul T. Kirschmeier, Donna Carr, Journal of Biological Chemistry	1997	202
Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors Thierry Fischmann, Catherine K. Smith, Todd Mayhood, Biochemistry Crystal StructureMolecular BiologyKinase Domain SpansMek1 BinarySignaling Pathway	2009	174
Novel Tricyclic Inhibitors of Farnesyl Protein Transferase W. Robert Bishop, Richard Bond, Joanne Petrin, Journal of Biological Chemistry	1995	155
Development of MK-8353, an orally administered ERK1/2 inhibitor, in patients with advanced solid tumors Stergios J. Moschos, Ryan J. Sullivan, Wen-Jen Hwu, JCI Insight	2018	145
Ras oncoprotein inhibitors: The discovery of potent, ras nucleotide exchange inhibitors and the structural determination of a drug-protein complex Arthur G. Taveras, Stacy Remiszewski, Ronald J. Doll, Bioorganic & Medicinal Chemistry Molecular DockingDrug TargetBiochemistryDrug-protein ComplexMedicine	1997	121
The Farnesyl Transferase Inhibitor SCH 66336 Induces a G2 → M or G1 Pause in Sensitive Human Tumor Cell Lines Hena R. Ashar, Linda James, Kimberly Gray, Experimental Cell Research Tumor BiologyG1 PauseOncogenic AgentMedicineCell Biology	2001	111
Exploring the Pharmacokinetic/Pharmacodynamic Relationship of Relebactam (MK-7655) in Combination with Imipenem in a Hollow-Fiber Infection Model Jin Wu, Fred Racine, Michael K. Wismer, Antimicrobial Agents and Chemotherapy	2018	61

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