Heidi Mangus

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Publications

Citations

226

H-Index

Active since

2015

Affiliations

Agios Pharmaceuticals (United States)(Current)

Pharmaceutical Product Development (United States)

Heidi Mangus is an author at Agios Pharmaceuticals (United States) specializing in biochemistry, mass spectrometric analysis, and bioanalytical method validation.

ORCID

Publications per year

2015–2023

Publications

A phase 1 dose escalation study of the pyruvate kinase activator mitapivat (AG-348) in sickle cell disease

Julia Xu, Anna Conrey, Ingrid Frey et al. · Blood · 2022 · 72 citations · Full text

Life Sciences, Pharmacotherapy, Cell Signaling +8

“Center punch” and “whole spot” bioanalysis of apixaban in human dried blood spot samples by UHPLC-MS/MS

Naiyu Zheng, Long Yuan, Qin Ji et al. · Journal of Chromatography B · 2015 · 50 citations

Natural Sciences, Biochemistry, Pharmaceutical Analysis +12

Decreased activity and stability of pyruvate kinase in sickle cell disease: a novel target for mitapivat therapy

Minke A.E. Rab, Jennifer Bos, Brigitte A. van Oirschot et al. · Blood · 2021 · 45 citations · Full text

Life Sciences, Biochemistry, Pharmacology +14

A double surrogate approach for the quantitation of 2-Hydroxyglutarate – An oncometabolite in human brain tumors via LC-MS/MS

Feng Yin, Jennifer M. Keller, Dennis H. Kraus et al. · Journal of Pharmaceutical and Biomedical Analysis · 2019 · 24 citations

Medicine, Biochemistry, Oncology +10

Quantitation of 2-Hydroxyglutarate in Human Plasma Via LC–MS/MS Using a Surrogate Analyte Approach

Feng Yin, Yonghua Ling, Jennifer M. Keller et al. · Bioanalysis · 2020 · 13 citations

Pharmacy, Biochemistry, Pharmacology +14

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