Itoro Akpan

Functional Nanoscale Organization of Signaling Molecules Downstream of the T Cell Antigen Receptor

Eilon Sherman, Valarie A. Barr, Suliana Manley et al. · Immunity · 2011 · 311 citations · Full text

Signal Transduction, T-regulatory Cell, Immunology +11

Recruitment of calcineurin to the TCR positively regulates T cell activation

Debjani Dutta, Valarie A. Barr, Itoro Akpan et al. · Nature Immunology · 2016 · 93 citations

T Cell Activation, Signal Transduction, Cell Signaling +8

Enhanced T-cell signaling in cells bearing linker for activation of T-cell (LAT) molecules resistant to ubiquitylation

Lakshmi Balagopalan, Benjamin A. Ashwell, Kelsie M. Bernot et al. · Proceedings of the National Academy of Sciences · 2011 · 59 citations

T-regulatory Cell, Immunology, Molecular Biology +18

The Ability of Sos1 to Oligomerize the Adaptor Protein LAT Is Separable from Its Guanine Nucleotide Exchange Activity in Vivo

Robert L. Kortum, Lakshmi Balagopalan, Clayton P. Alexander et al. · Science Signaling · 2013 · 49 citations · Full text

Multipoint Binding of the SLP-76 SH2 Domain to ADAP Is Critical for Oligomerization of SLP-76 Signaling Complexes in Stimulated T Cells

Nathan P. Coussens, Ryo Hayashi, Patrick H. Brown et al. · Molecular and Cellular Biology · 2013 · 48 citations · Full text

Signal Transduction Pathways, Molecular Biology, Signaling Pathway +16