Matthias Drosten

Tumours with class 3 BRAF mutants are sensitive to the inhibition of activated RAS

Zhan Yao, Rona Yaeger, Vanessa Rodrik-Outmezguine et al. · Nature · 2017 · 562 citations

Medicine, Genetics, Oncology +16

Genetic analysis of Ras signalling pathways in cell proliferation, migration and survival

Matthias Drosten, Alma Dhawahir, Eleanor Y. M. Sum et al. · The EMBO Journal · 2010 · 352 citations · Full text

Life Sciences, Cell Biology, Genetics +14

Allele-Specific Mechanisms of Activation of MEK1 Mutants Determine Their Properties

Yijun Gao, Matthew T. Chang, Daniel J. McKay et al. · Cancer Discovery · 2018 · 148 citations · Full text

Medicine, Cancer Biology, Oncology +17

Mutant K-Ras Activation of the Proapoptotic MST2 Pathway Is Antagonized by Wild-Type K-Ras

David Matallanas, David Romano, Fahd Al‐Mulla et al. · Molecular Cell · 2011 · 139 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Complete Regression of Advanced Pancreatic Ductal Adenocarcinomas upon Combined Inhibition of EGFR and C-RAF

Maria Blasco, Carolina Navas, Guillermo Martín‐Serrano et al. · Cancer Cell · 2019 · 121 citations · Full text

Medicine, Oncology, Pharmacology +9