Markus G. Grütter

High-affinity binders selected from designed ankyrin repeat protein libraries

Hans Binz, Patrick Amstutz, A. Kohl et al. · Nature Biotechnology · 2004 · 667 citations

Pharmacy, Medicinal Chemistry, Molecular Biology +14

TRIM5 is an innate immune sensor for the retrovirus capsid lattice

Thomas Pertel, Stéphane Hausmann, Damien Morger et al. · Nature · 2011 · 657 citations · Full text

Life Sciences, Immunology, Molecular Biology +14

Structure-based design of aliskiren, a novel orally effective renin inhibitor

Jeanette M. Wood, Jürgen Maibaum, Joseph Rahuel et al. · Biochemical and Biophysical Research Communications · 2003 · 503 citations

Pharmacy, Medicinal Chemistry, Pharmacology +14

The Long Form of FLIP Is an Activator of Caspase-8 at the Fas Death-inducing Signaling Complex

Olivier Micheau, Margot Thome, Pascal Schneider et al. · Journal of Biological Chemistry · 2002 · 472 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Precision is essential for efficient catalysis in an evolved Kemp eliminase

Rebecca Blomberg, Hajo Kries, Daniel M. Pinkas et al. · Nature · 2013 · 347 citations · Full text

Life Sciences, Biochemistry, Biology +14