Valproic acid exposure sequentially activates Wnt and mTOR pathways in rats

Liyan Qin, Xufang Dai, Yunhou Yin

Molecular and Cellular Neuroscience

MedicinePhysiologyExperimental PharmacologyPharmacotherapyNeuroscience +5

The novel BH-3 mimetic apogossypolone induces Beclin-1- and ROS-mediated autophagy in human hepatocellular carcinoma cells

Ping Cheng, Zhenhong Ni, Xufang Dai, +7

Cell Death and Disease

MitophagyRos-mediated AutophagyApoptosisImmunologyCell Death +15

HCC cells with high levels of Bcl-2 are resistant to ABT-737 via activation of the ROS–JNK–autophagy pathway

Zhenhong Ni, Bin Wang, Xufang Dai, +7

Free Radical Biology and Medicine

Cell AutophagySignal TransductionSignaling PathwayCell RegulationApoptosis +10

The Bcl-2/xL inhibitor ABT-263 increases the stability of Mcl-1 mRNA and protein in hepatocellular carcinoma cells

Bin Wang, Zhenhong Ni, Xufang Dai, +5

Molecular Cancer

AKT-mediated phosphorylation of ATG4B impairs mitochondrial activity and enhances the Warburg effect in hepatocellular carcinoma cells

Zhenhong Ni, Jintao He, Yaran Wu, +12

Autophagy

Sorafenib Sensitizes (−)-Gossypol-Induced Growth Suppression in Androgen-Independent Prostate Cancer Cells via Mcl-1 Inhibition and Bak Activation

Jiqin Lian, Zhenhong Ni, Xufang Dai, +4

Molecular Cancer Therapeutics

Bak ActivationApoptosis InductionSorafenib AttenuatesMedicineGrowth Suppression +12

Targeting the <i>MIR34C-5p</i>-ATG4B-autophagy axis enhances the sensitivity of cervical cancer cells to pirarubicin

Yaran Wu, Zhenhong Ni, Xiaojing Yan, +5

Autophagy

ImmunologyCell DeathCancer BiologyTumor BiologyCell Autophagy +14

LncRNA CRNDE Promotes ATG4B-Mediated Autophagy and Alleviates the Sensitivity of Sorafenib in Hepatocellular Carcinoma Cells

Lingxi Chen, Liangbo Sun, Xufang Dai, +14

Frontiers in Cell and Developmental Biology

Deacetylation of ATG4B promotes autophagy initiation under starvation

Liangbo Sun, Haojun Xiong, Lingxi Chen, +11

Science Advances

AU4S: A novel synthetic peptide to measure the activity of ATG4 in living cells

Zhenhong Ni, Yi Gong, Xufang Dai, +8

Autophagy