Lyuben Tsvetkov

p27Kip1 ubiquitination and degradation is regulated by the SCFSkp2 complex through phosphorylated Thr187 in p27

Lyuben Tsvetkov, Kun‐Huei Yeh, Soo-Jung Lee et al. · Current Biology · 1999 · 786 citations · Full text

The BRAF and MEK Inhibitors Dabrafenib and Trametinib: Effects on Immune Function and in Combination with Immunomodulatory Antibodies Targeting PD-1, PD-L1, and CTLA-4

Li Liu, Patrick A. Mayes, Stephen D. Eastman et al. · Clinical Cancer Research · 2015 · 440 citations

PTEN regulates the ubiquitin-dependent degradation of the CDK inhibitor p27KIP1 through the ubiquitin E3 ligase SCFSKP2

Ramanaiah Mamillapalli, Nadia J. Gavrilova, Valia T. Mihaylova et al. · Current Biology · 2001 · 224 citations · Full text

Cdk Inhibitor P27kip1, Signal Transduction, Signaling Pathway +9

Tumor-immune profiling of murine syngeneic tumor models as a framework to guide mechanistic studies and predict therapy response in distinct tumor microenvironments

Jong W. Yu, Sabyasachi Bhattacharya, Niranjan Yanamandra et al. · PLoS ONE · 2018 · 197 citations · Full text

Unique Tumor-immune Infiltrate, Novel Anti-cancer Immunotherapies, Immunology +17

Chk2 Activation and Phosphorylation-Dependent Oligomerization

Xingzhi Xu, Lyuben Tsvetkov, David F. Stern · Molecular and Cellular Biology · 2002 · 182 citations · Full text