Mianzhi Zhang

Legumain promotes tubular ferroptosis by facilitating chaperone-mediated autophagy of GPX4 in AKI

Chuan’ai Chen, Dekun Wang, Yangyang Yu et al. · Cell Death and Disease · 2021 · 288 citations · Full text

Medicine, Pathobiology, Pathology +16

Legumain, an asparaginyl endopeptidase, mediates the effect of M2 macrophages on attenuating renal interstitial fibrosis in obstructive nephropathy

Dekun Wang, Min Xiong, Chuan’ai Chen et al. · Kidney International · 2018 · 65 citations

Medicine, Immunology, Nephrology +15

Schisandra chinensis fruit extract attenuates albuminuria and protects podocyte integrity in a mouse model of streptozotocin-induced diabetic nephropathy

Mianzhi Zhang, Miao Liu, Min Xiong et al. · Journal of Ethnopharmacology · 2012 · 42 citations

Medicine, Biochemistry, Nephrology +11

Legumain-deficient macrophages promote senescence of tumor cells by sustaining JAK1/STAT1 activation

Long Shen, Lichun Kang, Dekun Wang et al. · Cancer Letters · 2019 · 42 citations

Life Sciences, Immunology, Oncology +12

Causal effects of systemic inflammatory regulators on chronic kidney diseases and renal function: a bidirectional Mendelian randomization study

Hongdian Li, Mingxuan Li, Cong Liu et al. · Frontiers in Immunology · 2023 · 39 citations · Full text

Medicine, Biostatistics, Immunology +15