David Lyden

Tumour exosome integrins determine organotropic metastasis

Ayuko Hoshino, Bruno Costa‐Silva, Tang‐Long Shen et al. · Nature · 2015 · 4.9K citations · Full text

Medicine, Pathology, Cell-matrix Interaction +6

Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

Héctor Peinado, Maša Alečković, Simon Lavotshkin et al. · Nature Medicine · 2012 · 3.6K citations · Full text

Exosomes, Medicine, Melanoma +12

VEGFR1-positive haematopoietic bone marrow progenitors initiate the pre-metastatic niche

Rosandra N. Kaplan, Rebecca D. Riba, Stergios Zacharoulis et al. · Nature · 2005 · 3.2K citations · Full text

Pre-metastatic Niche, Stem Cell Mobilization, Biological Microenvironments +4

Pancreatic cancer exosomes initiate pre-metastatic niche formation in the liver

Bruno Costa‐Silva, Nicole M. Aiello, Allyson J. Ocean et al. · Nature Cell Biology · 2015 · 2.6K citations · Full text

Tumor Biology, Pancreatic Cancer, Hepatology +12

Impaired recruitment of bone-marrow–derived endothelial and hematopoietic precursor cells blocks tumor angiogenesis and growth

David Lyden, Koichi Hattori, Sérgio Dias et al. · Nature Medicine · 2001 · 1.9K citations

Angiogenesis, Medicine, Stem Cell Mobilization +11