Reconstituted NALP1 Inflammasome Reveals Two-Step Mechanism of Caspase-1 Activation

Benjamin Faustin, Lydia Lartigue, Jean‐Marie Bruey, +7

Molecular Cell

InflammationSignal TransductionSignaling PathwayCell DeathInflammasome +6

Mutant huntingtin binds the mitochondrial fission GTPase dynamin-related protein-1 and increases its enzymatic activity

Wenjun Song, Jin Chen, Alejandra M. Petrilli, +14

Nature Medicine

MitophagySignal TransductionMitochondrial FunctionEnzymatic ActivityMitochondrial Dynamic +6

Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy

Gian‐Luca McLelland, Thomas Goiran, Wei Yi, +10

eLife

MitophagyMolecular BiologyCell DeathCytoskeletonOxidative Stress +18

The structural basis of actin filament branching by the Arp2/3 complex

Isabelle Rouiller, Xiao-Ping Xu, Kurt J. Amann, +7

The Journal of Cell Biology

Protein AssemblyMolecular BiologyCytoskeletonBranched Actin FilamentsProtein Folding +16

“Breathing” Vesicles

Shaoyong Yu, Tony Azzam, Isabelle Rouiller, +1

Journal of the American Chemical Society

The Peptidisc, a simple method for stabilizing membrane proteins in detergent-free solution

Michael Luke Carlson, John William Young, Zhiyu Zhao, +11

eLife

Conformational changes of the multifunction p97 AAA ATPase during its ATPase cycle

Isabelle Rouiller, Byron DeLaBarre, Andrew P. May, +4

Nature Structural Biology

BiochemistryProtein FoldingNatural SciencesMolecular BiologyConformational Changes +7

Mechanistic Differences in Actin Bundling Activity of Two Mammalian Formins, FRL1 and mDia2

Elizabeth S. Harris, Isabelle Rouiller, Dorit Hanein, +1

Journal of Biological Chemistry

Actin Bundling ActivityMechanistic DifferencesProtein AssemblyMolecular BiologyCytoskeleton +15

Metal–nucleic acid cages

Hua Yang, Christopher K. McLaughlin, Faisal A. Aldaye, +4

Nature Chemistry

Dna NanotechnologyNucleic Acid ChemistryNatural SciencesNucleic Acid BiochemistryMetal–nucleic Acid Cages +2

A Major Conformational Change in p97 AAA ATPase upon ATP Binding

Isabelle Rouiller, Virginia M. Butel, Martin Latterich, +2

Molecular Cell

Cellular EnzymologyBiochemistryProtein FoldingNatural SciencesMolecular Biology +9