S.E. Greasley - Concepedia

Concepedia

Author

S.E. Greasley

Pfizer (United States)ORCID

Also Known As

Kim Frederix, S. E. Greasley, S. Greasley, S.E. Greasley, Samantha E Greasley, Samantha E. Greasley, Samantha Greasley

59

Publications

3.6K

Citations

29

H-Index

44

Concepts

All Affiliations

Pfizer (United States)Scripps Research Institute Pennsylvania State University Utah State University Yale University

SG

About

S.E. Greasley is an author at Pfizer (United States) specializing in medicine, pharmacology, and drug discovery.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	16	17	2.5K
2	Biochemistry	11	11	551
3	Natural Sciences	9	9	467
4	Health Sciences	1	1	35
5	Cell Biology	1	1	65

S.E. Greasley

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35

Publications

3.6K

Citations

29

H-Index

	Year	Citations
An oral SARS-CoV-2 M <sup>pro</sup> inhibitor clinical candidate for the treatment of COVID-19 Dafydd R. Owen, Charlotte Allerton, Annaliesa S. Anderson, Science Viral DiagnosticsWorldwide OutbreakImmunologyImmunotherapeuticsCovid-19 Epidemiology	2021	1.8K
Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants S.E. Greasley, Stephen Noell, Olga Plotnikova, Journal of Biological Chemistry	2022	168
Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1<i>H</i>-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate Stefano Crosignani, Patrick Bingham, Pauline Bottemanne, Journal of Medicinal Chemistry	2017	134
The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms S.E. Greasley, Harren Jhoti, Carmel G. Teahan, Nature Structural & Molecular Biology Protein ChemistryProtein FunctionBiochemistryProtein AssemblyRat Adp-ribosylation Factor-1	1995	106
Structure-based design of novel human Pin1 inhibitors (I) Chuangxing Guo, Xinjun Hou, Liming Dong, Bioorganic & Medicinal Chemistry Letters Molecular DockingDrug TargetMedicineRational Drug DesignStructure-based Design	2009	105
Structure-based design of novel human Pin1 inhibitors (II) Liming Dong, Joseph Marakovits, Xinjun Hou, Bioorganic & Medicinal Chemistry Letters Molecular DockingDrug TargetMedicineRational Drug DesignStructure-based Design	2010	86
Crystal structure of a bifunctional transformylase and cyclohydrolase enzyme in purine biosynthesis. S.E. Greasley, Patricia A. Horton, Joseph Ramcharan, Nature Structural Biology Crystal StructureBiosynthesisBiochemistryNatural SciencesBiocatalysis	2001	82
Discovery of Aryloxy Tetramethylcyclobutanes as Novel Androgen Receptor Antagonists Chuangxing Guo, Angelica Linton, Susan E. Kephart, Journal of Medicinal Chemistry	2011	67
Insights into Mechanism of Glucokinase Activation Shenping Liu, Mark Ammirati, Xi Song, Journal of Biological Chemistry Protein FunctionSignal TransductionMolecular PhysiologyBiochemistryG Protein-coupled Receptor	2012	65
Discovery of a highly potent, selective, orally bioavailable inhibitor of KAT6A/B histone acetyltransferases with efficacy against KAT6A-high ER+ breast cancer Shikhar Sharma, Chi‐Yeh Chung, Sean Uryu, Cell chemical biology	2023	59

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