S.E. Greasley

An oral SARS-CoV-2 M ^pro inhibitor clinical candidate for the treatment of COVID-19

Dafydd R. Owen, Charlotte Allerton, Annaliesa S. Anderson et al. · Science · 2021 · 1.8K citations · Full text

Viral Diagnostics, Worldwide Outbreak, Immunology +16

Structural basis for the in vitro efficacy of nirmatrelvir against SARS-CoV-2 variants

S.E. Greasley, Stephen Noell, Olga Plotnikova et al. · Journal of Biological Chemistry · 2022 · 168 citations · Full text

Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3-(5-Fluoro-1<i>H</i>-indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as a Potential Clinical Candidate

Stefano Crosignani, Patrick Bingham, Pauline Bottemanne et al. · Journal of Medicinal Chemistry · 2017 · 134 citations · Full text

The structure of rat ADP-ribosylation factor-1 (ARF-1) complexed to GDP determined from two different crystal forms

S.E. Greasley, Harren Jhoti, Carmel G. Teahan et al. · Nature Structural & Molecular Biology · 1995 · 106 citations

Protein Chemistry, Protein Function, Biochemistry +7

Structure-based design of novel human Pin1 inhibitors (I)

Chuangxing Guo, Xinjun Hou, Liming Dong et al. · Bioorganic & Medicinal Chemistry Letters · 2009 · 105 citations · Full text

Molecular Docking, Drug Target, Medicine +4