Alexander Arlt

Role of NF-κB and Akt/PI3K in the resistance of pancreatic carcinoma cell lines against gemcitabine-induced cell death

Alexander Arlt, André Gehrz, Susanne Sebens Müerköster et al. · Oncogene · 2003 · 473 citations

Medicine, Cell Biology, Oncology +14

Inhibition of the Nrf2 transcription factor by the alkaloid trigonelline renders pancreatic cancer cells more susceptible to apoptosis through decreased proteasomal gene expression and proteasome activity

Alexander Arlt, Susanne Sebens, Stefan Krebs et al. · Oncogene · 2012 · 327 citations

Life Sciences, Oncology, Pharmacology +16

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

Felix Stickel, Stephan Buch, Katharina Lau et al. · Hepatology · 2010 · 285 citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Tumor Stroma Interactions Induce Chemoresistance in Pancreatic Ductal Carcinoma Cells Involving Increased Secretion and Paracrine Effects of Nitric Oxide and Interleukin-1β

Susanne Sebens Müerköster, Kai Wegehenkel, Alexander Arlt et al. · Cancer Research · 2004 · 254 citations

Medicine, Cell Biology, Oncology +17

Increased proteasome subunit protein expression and proteasome activity in colon cancer relate to an enhanced activation of nuclear factor E2-related factor 2 (Nrf2)

Alexander Arlt, Iris Bauer, Clemens Schafmayer et al. · Oncogene · 2009 · 250 citations

Medicine, Molecular Biology, Oncology +13