Genome-wide association scan identifies a colorectal cancer susceptibility locus on 11q23 and replicates risk loci at 8q24 and 18q21

Albert Tenesa, Susan M. Farrington, James Prendergast, +54

Nature Genetics

Genome-wide Association StudyGenome-wide AssociationColorectal Cancer SusceptibilityGeneticsColorectal Cancer +6

A genome-wide association study identifies colorectal cancer susceptibility loci on chromosomes 10p14 and 8q23.3

Ian PM Tomlinson, Emily L. Webb, Luis G. Carvajal‐Carmona, +71

Nature Genetics

Cancer SusceptibilityGenome-wide Association StudyChromosomes 10P14MedicineGenetics +8

A genome-wide association study confirms PNPLA3 and identifies TM6SF2 and MBOAT7 as risk loci for alcohol-related cirrhosis

Stephan Buch, Felix Stickel, Eric Trépo, +44

Nature Genetics

Genome-wide Association StudyHepatologyMedicineLiver PhysiologyGenetics +8

A genome-wide association scan identifies the hepatic cholesterol transporter ABCG8 as a susceptibility factor for human gallstone disease

Stephan Buch, Clemens Schafmayer, Henry Völzke, +23

Nature Genetics

Metabolic SyndromeGenome-wide AssociationHepatologySusceptibility FactorBiliary Tract +11

Genetic variation in the PNPLA3 gene is associated with alcoholic liver injury in caucasians

Felix Stickel, Stephan Buch, Katharina Lau, +29

Hepatology

Cumulative Burden of Colorectal Cancer–Associated Genetic Variants Is More Strongly Associated With Early-Onset vs Late-Onset Cancer

Alexi Archambault, Yu‐Ru Su, Jihyoun Jeon, +131

Gastroenterology

Cancer RiskCancer EpidemiologyMedicineGeneticsCumulative Burden +7

Heterozygous carriage of the alpha1-antitrypsin Pi*Z variant increases the risk to develop liver cirrhosis

Pavel Strnad, Stephan Buch, Karim Hamesch, +57

Gut

Genome-wide association analysis of diverticular disease points towards neuromuscular, connective tissue and epithelial pathomechanisms

Clemens Schafmayer, Stephan Buch, Christina Lange, +58

Gut

Loss of hepatic Mboat7 leads to liver fibrosis

Veera Raghavan Thangapandi, Oskar Knittelfelder, Mario Brosch, +28

Gut

Predictors of gallstone composition in 1025 symptomatic gallstones from Northern Germany

Clemens Schafmayer, Jürgen Hartleb, Jürgen Tepel, +12

BMC Gastroenterology