Oral Bruton tyrosine kinase inhibitors selectively block atherosclerotic plaque–triggered thrombus formation in humans

Kristina Busygina, Janina Jamasbi, Till Seiler, +5

Blood

Cathepsin G Controls Arterial But Not Venular Myeloid Cell Recruitment

Almudena Ortega‐Gómez, Melanie Salvermoser, Jan Rossaint, +17

Circulation

Differential Inhibition of Human Atherosclerotic Plaque–Induced Platelet Activation by Dimeric GPVI-Fc and Anti-GPVI Antibodies

Janina Jamasbi, Remco T. A. Megens, Mariaelvy Bianchini, +12

Journal of the American College of Cardiology

Oral thrombin inhibitor aggravates platelet adhesion and aggregation during arterial thrombosis

Tobias Petzold, Manuela Thienel, Ildiko Konrad, +14

Science Translational Medicine

Optimizing Platelet GPVI Inhibition versus Haemostatic Impairment by the Btk Inhibitors Ibrutinib, Acalabrutinib, ONO/GS-4059, BGB-3111 and Evobrutinib

Viola Denzinger, Kristina Busygina, Janina Jamasbi, +5

Thrombosis and Haemostasis

Recombinant GPVI-Fc added to single or dual antiplatelet therapy in vitro prevents plaque-induced platelet thrombus formation

Ann‐Katrin Mojica Munoz, Janina Jamasbi, Kerstin Uhland, +8

Thrombosis and Haemostasis

Dimeric Glycoprotein VI Binds to Collagen but Not to Fibrin

Mariam Ebrahim, Janina Jamasbi, Kristin Adler, +11

Thrombosis and Haemostasis

ADPase CD39 Fused to Glycoprotein VI‐Fc Boosts Local Antithrombotic Effects at Vascular Lesions

Heidrun Degen, Oliver Borst, M. Ziégler, +12

Journal of the American Heart Association

Glycoprotein VI is not a Functional Platelet Receptor for Fibrin Formed in Plasma or Blood

Danmei Zhang, Mariam Ebrahim, Kristin Adler, +11

Thrombosis and Haemostasis

Stereo specific platelet inhibition by the natural LXR agonist 22(R)-OH-cholesterol and its fluorescence labelling with preserved bioactivity and chiral handling in macrophages

Stephanie Schaffer, Raman Tandon, Hendrik Zipse, +6

Biochemical Pharmacology